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HB 4778

Health: immunizations; administration of gene-based vaccines; prohibit. Amends secs. 9201 & 16221 of 1978 PA 368 (MCL 333.9201 & 333.16221) & adds sec. 9228.

2025-2026 Regular Session Introduced by Jaime Greene and 6 co-sponsors

Michigan bill prohibits administering gene-based vaccines, restricting mRNA and similar vaccine technologies' availability in the state.

bill electronically reproduced 08/20/2025
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Bill Summary · HB 4778

Legislative bill overview

HB 4778 proposes to amend Michigan's Public Health Code to prohibit the administration of gene-based vaccines within the state. The bill modifies existing sections governing immunization requirements and adds new language to establish restrictions on this vaccine category.

Why is this important

This legislation would directly affect vaccine availability and public health policy in Michigan by potentially removing access to an emerging class of vaccines, including mRNA-based vaccines (such as COVID-19 and influenza vaccines). The bill's scope could impact routine immunization programs, disease prevention strategies, and Michigan's participation in federal vaccination initiatives.

Potential points of contention

  • Definition and scope: The bill doesn't provide a clear definition of "gene-based vaccines," creating ambiguity about which vaccines would be prohibited (mRNA vaccines, viral vector vaccines, DNA-based vaccines, or others)
  • Public health authority conflict: The restriction may conflict with federal CDC recommendations and FDA-approved vaccines, raising questions about state versus federal regulatory authority
  • Disease prevention gaps: Restricting access to certain vaccine technologies could limit options for controlling infectious diseases, particularly novel pathogens where gene-based vaccines are the primary available tool

Compiled from official sources — confirm details with the bill’s official record.

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