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Bill

Bill

SB 410

CRYSTALLINE POLYMORPH PSILOCYBIN RESCHEDULING

2025 Regular Session Introduced by Craig Brandt

New Mexico bill would reschedule crystalline polymorph psilocybin from Schedule I, potentially enabling medical research but creating federal-state drug policy conflict.

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Bill Summary · SB 410

Legislative bill overview

SB 410 would reschedule crystalline polymorph psilocybin from a Schedule I controlled substance to a different legal classification in New Mexico. This targets a specific chemical form of psilocybin rather than psilocybin broadly, potentially creating a regulatory pathway for research or therapeutic use of this particular variant.

Why is this important

Psilocybin rescheduling could enable clinical research into its potential therapeutic applications for mental health conditions like depression, PTSD, and end-of-life anxiety—areas where early research shows promise. However, this also represents a significant departure from federal drug policy and raises questions about state-level drug scheduling authority and implementation challenges.

Potential points of contention

  • Crystalline polymorph specificity: The bill's focus on one specific chemical form creates ambiguity about whether other psilocybin forms remain Schedule I, potentially creating enforcement and legal loopholes
  • Federal-state conflict: Psilocybin remains a Schedule I drug federally; state rescheduling could create jurisdictional conflicts and complicate interstate commerce/research protocols
  • Therapeutic framework uncertainty: The bill doesn't clearly establish whether rescheduling enables medical use, research only, or decriminalization, creating regulatory confusion

Compiled from official sources — confirm details with the bill’s official record.

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